Project A1: Dynamics and control of multi-site communication in the brain
Prof. Dr. Claus Hilgetag
Dept. of Computational Neuroscience, UKE
The project aims to understand fundamental mechanisms of network dynamics in intact as well as perturbed and modulated neural networks through computational analysis and modeling, and to apply these insights to specific networks of the ferret and human brain. Two central aspects of multi-site communication will be considered, first, the integration of inter-regional anatomical connectivity with local brain architecture and its implications for normal brain dynamics, and, second, mechanisms of network control and their implications for understanding functional deficits in brains that are pathologically impaired (e.g., by stroke) as well as for the experimental modulation of brain dynamics.